Entrectinib Impresses in Certain Lung Cancers Durable responses in most patients with advanced NSCLC, active in brain mets Mar 05, 2021
Can PARP Inhibitor Eligibility Expand in Pancreatic Cancer? Two trials show limited activity in patients with "BRCAness" Mar 05, 2021
Birth Weight, IGF-1, and Adult Diabetes Go Hand in Hand Is mid-life metabolic future foretold at birth? Mar 01, 2021
Op-Ed: Here's How We Should Approach Coronavirus Variant Tracking Scattershot sequencing won't help -- nation needs a strategy Feb 17, 2021
ANGPTL-3 Inhibitor OK'd for Ultra-Rare Lipid Disorder Approval based on the small ELIPSE trial Feb 11, 2021
Decipher Test May Guide Post-Surgical Tx in Prostate Cancer Another step toward personalized therapy? Feb 11, 2021
Oncotype DX Misses on Breast Cancer Risk in Black Women Accuracy of 21-gene recurrence score worse compared with white women Jan 21, 2021
Not Just BRCA: Large Studies ID Other Key Breast Cancer Risk Genes Implications for screening and other risk-management strategies, researchers say Jan 20, 2021
FDA Drowned in 'Junk Science'; Sorting Out COVID Variants; Vax Distribution Chaos This past week in healthcare investigations Jan 20, 2021
Fraudster Convicted in Senior Genetic Testing Scam Doctors approved tests via telemedicine for patients they never saw Jan 13, 2021
Broader Role for PARP Inhibitors in Breast Cancer? Responses in tumors with somatic or germline mutations related to HRD Dec 14, 2020
Online Tool Refines Individual Risks in Breast Cancer RSClin incorporates 21-gene recurrence score with tumor grade, size, and more Dec 13, 2020
MC4 Agonist Cuts Body Weight, Hunger in Genetically-Driven Obesity Trial success raises questions about broader application Nov 04, 2020
Military Burn Pits Linked With RA Seropositivity Highest risks for anti-CCP antibodies seen for smokers and those with the HLA-DRB1 shared epitope genes Oct 23, 2020
Win for PARP Inhibitor in BRCA Breast Cancer Veliparib maintenance after stopping chemo credited with modest PFS gain Sep 01, 2020
Which Women Choose Hormones for Surgical Menopause? Understanding patterns of use can help improve targeting for education and counseling, researchers say Aug 12, 2020
Dementia Tied to Olfaction; Preclinical Alzheimer's Trial; Guillain-Barré and COVID-19 News and commentary from the world of neurology and neuroscience Jul 21, 2020
Consider Genetic Testing in All Metastatic Prostate Cancers Expert panel recommends testing for men with family history, selective testing for others Jun 10, 2020
Does G6PD Deficiency Relate to COVID-19 Infection? Several hints of one, pointing to need for focused research Apr 13, 2020
COVID-19 Susceptibility: Why Do Some Become So Ill? Mark Jay Zucker, MD, JD, considers genetics as a factor Apr 03, 2020
Two Regimens Active in BRCA+ Triple-Negative Breast Cancer Study shows no superiority for platinum-containing chemotherapy Mar 18, 2020
Gene Score Alone Little Help in Guiding Prostate Cancer Surveillance Tool should be used to predict risk together with all known clinical and pathologic parameters Mar 09, 2020
First In-Human CRISPR Gene-Editing Performed Procedure a "milestone moment" for the gene editing field, expert says Mar 06, 2020
What's Holding Back Gene Therapy? Quality control, manufacturing capacity loom as obstacles Feb 19, 2020
The 'Living Drug' Changing How Cancer Is Treated And the "forks in the road" that led to the discovery of CAR T-cell therapy Jan 21, 2020
SCOTUS Punts on Biomarker Test Patents Wide-ranging issue effectively referred to Congress Jan 13, 2020
Diagnosing HFpEF and Cardiac Amyloidosis Don't think about HFpEF as a clinical syndrome in isolation, says Frederick Ruberg, MD Jan 04, 2020 podcast
How an Ancient Virus Spread the Ability to Remember Genetics may hold the key to human cognition Dec 13, 2019
IGHV-Unmutated CLL: Gene Signature May Predict Outcomes After First-Line FCR Prognostic tool may predict who is likely to achieve a relatively long remission Oct 15, 2019
Deaf Parents Want Deaf Baby: Bioethicist Weighs In You voted, now see the results and an expert's discussion Oct 11, 2019
Mila's N-of-1 Trial Detailed in NEJM Neurologic scores stabilized, seizures diminished with tailored antisense oligonucleotide therapy Oct 09, 2019
FCR Still an Option in IGHV-Unmutated CLL? Gene signature identifies lower-risk group with greater chemoimmunotherapy benefit Oct 08, 2019
Ethics Consult: Deaf Couple Only Wants Deaf Baby You make the call: should doctor implant embryo selected for deafness? Oct 04, 2019
Faulty Amino Acid Metabolism Linked to Rare Eye Disease Study helps explain genetic heterogeneity in macular telangiectasia type 2 Sep 12, 2019
Good News, Bad News for CRISPR Gene Editing for HIV Cure "Bigger story for the gene-editing field than the HIV field" Sep 11, 2019
The Legacy of Henry Lynch, MD Earlier this summer the legendary researcher passed, his contributions to cancer research are immeasurable Sep 01, 2019
Desperate Families Pursue 'N-of-1' Trials for Ultra-Rare Diseases Technology dangles hope of cure -- for those able to pay Aug 21, 2019
The Alzheimer's-Cholesterol Connection Parallel lines of evidence link the two in early-onset Alzheimer's disease May 28, 2019