After Rejection, Tenapanor for Kidney Disease Faces FDA's Outside Experts Drug's effect on serum phosphorus "small and of unclear clinical significance," say FDA reviewers Nov 15, 2022
Outdoor Lighting at Night Tied to Diabetes Prevalence China study may have global implications for diabetes risk Nov 14, 2022
COVID Reinfection More Lethal; No, Insulin Is Not 'Free' Now; 1 in 9 Teens Smoking Health news and commentary from around the Web gathered by MedPage Today staff Nov 11, 2022
Low-Dose 'Quadpill' Reduces High Blood Pressure Significantly lower diastolic blood pressure at 12 weeks, U.S.-based study showed Nov 09, 2022
Strong Showing for Novel BP-Lowering Drugs in Resistant Hypertension Aprocitentan targets the endothelin pathway, whereas baxdrostat blocks aldosterone production Nov 09, 2022
Saline Goes Head-to-Head With Balanced Crystalloid IV Fluids for Kidney Transplant Researcher argued saline should be reconsidered as the standard IV fluid used Nov 07, 2022
Upfront ECMO Disappoints for Cardiogenic Shock High-cost procedure not yet justified as an early strategy Nov 07, 2022
Moving Fast on HF Drugs After Acute Hospitalization Holds Big Outcome Benefit Randomized trial shows advantages across heart failure spectrum Nov 07, 2022
Experts Agree Intravenous Iron Shows Promise for Heart Failure Patients While findings were not significant, the study was impacted by COVID lockdowns, researcher says Nov 07, 2022
Earlier Terlipressin May Be Better for HRS-AKI in Acute-on-Chronic Liver Failure More acute kidney injury reversals at 7 days and lower mortality with initiation at 12 hours Nov 07, 2022
Mixed Results With Alerts for AKI-Related Medications in Hospital EHR pings improved outcomes in those on PPIs, but lacked general clinical impact Nov 06, 2022
Decision-Support Tool Enhances Outcomes for Heart Failure Patients in the ED Pathways for HF patients picked for early discharge versus admission Nov 06, 2022
Diuretics on Par in Head-to-Head Comparison for Hypertension But a surprise signal emerges for one group in pragmatic trial Nov 06, 2022
Mixed Results With Pemafibrate in Patients With Type 2 Diabetes No impact on CV events in PROMINENT; developer brings trial to an end Nov 06, 2022
Not So Cool After All: No CV Benefit With Lower-Temp Dialysate in Hemodialysis Some patients in MyTEMP trial even complained cooler dialysate was "worst possible feeling" Nov 06, 2022
Furosemide Holds Up to Newer, Stronger Loop Diuretic During HF Hospitalization Preference for mainstay decongestant versus torsemide likely unchanged after TRANSFORM-HF study Nov 05, 2022
Psilocybin for Depression; What's the Best Direct Oral Anticoagulant? Also in TTHealthWatch: hormone therapy to prevent chronic disease Nov 05, 2022 podcast
Empagliflozin Protects At-Risk Patients From CKD Progression Also cut risk for cardiovascular-related death and worsening kidney function Nov 04, 2022
Stop RAS Inhibitors in Advanced CKD? STOP ACEi Trial Sheds Some Light Findings do not support discontinuation to improve kidney function, researchers say Nov 03, 2022
Surveying Sewage for Polio; Physical Activity and COVID Vaccines Also in TTHealthWatch: maternal hypertension and offspring mortality Oct 29, 2022 podcast
FDA Panel Gives Thumbs Up to Anemia Pill for CKD Patients on Dialysis But thumbs quickly turn down for the non-dialysis subset Oct 27, 2022
Low-Carb Diet Helps Cut HbA1c in Prediabetes Could be a useful approach for preventing, treating type 2 diabetes, says researcher Oct 26, 2022
New HRS Drug Cuts Need for Renal Replacement Tx After Liver Transplant Follow-up data from CONFIRM trial show terlipressin benefit in key subgroup Oct 25, 2022
Another CKD-Related Anemia Drug Goes Under the Microscope of FDA Advisors After a panel turned down roxadustat last year, will daprodustat be recommended for approval? Oct 25, 2022
Outpatient Centers Cautiously Open Doors to Surgery for People With Cardiac Devices Will those with CIEDs become regular patients at ambulatory surgery centers within a decade? Oct 25, 2022
Insulin Rationing Common Among Patients With Diabetes More than a million Americans may be engaging in the risky practice, researchers said Oct 17, 2022
Childhood Obesity and a Mother's Diet; Neurodegenerative Disease in Rugby Players Also in TTHealthWatch: a new way to diagnose idiopathic pulmonary fibrosis Oct 15, 2022 podcast
Despite Exciting Newcomer Drugs, Uptake of HF Meds Still Meek Across Oceans U.S. not alone in slow initiation, low target-dose achievement, and early discontinuation Oct 14, 2022
Diabetes-Related CKD Rates Dropped Slightly in Recent Years But high incidence, especially in certain racial groups, remains a concern Oct 12, 2022
Pathology Labs Making Progress on Removing Race for Kidney Function Estimates Change will increase number of Black patients eligible for kidney transplant, medication regimens Oct 11, 2022
The Kidney Transplant Ecosystem Is Ripe for Reform Here are the policies and payment systems that need to change Oct 11, 2022
Lower Entresto Doses Suffice in the Real World Reassuring findings for patients who don't tolerate the maximum ARNI dose Oct 10, 2022
FDA Approves At-Home Furosemide for Heart Failure Strong diuretic to become available outside the hospital setting Oct 10, 2022
Can Eyes Predict CVD Mortality?; ICUs in the ED Also in TTHealthWatch: preventing stroke in TAVR and first-line therapy for type 2 diabetes Oct 08, 2022 podcast
CMS' Financial Incentives Didn't Move the Dial on Home Dialysis Incentives may just not be strong enough, say some Oct 07, 2022
Intermittently Scanned CGM Reduced HbA1c in Type 1 Diabetes The system offers optional high and low blood glucose alarms Oct 05, 2022
Salt Pills During Diuresis: Acute HF Patients Neither Helped Nor Harmed Small randomized trial challenges conventional thinking about sodium Oct 05, 2022
The Search Is On for Another Xeno Heart Transplant Recipient Transplant surgeons discuss testing the concept in more humans Oct 04, 2022
SGLT2 Inhibitors, GLP-1 RAs Not Cost-Effective as First-Line T2D Agents Cost-effectiveness study compared lifetime costs with first-line metformin Oct 03, 2022
Urgency to Expand SGLT2i Use in HF Heightened by More DELIVER Data Analyses continue to support wider adoption of dapagliflozin, researchers say Oct 03, 2022