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News, opinions and meeting coverage in dermatology.

AAD over a photo of Ernest N. Morial Convention Center in New Orleans, Louisiana.

Durable Vitiligo Responses With Topical Ruxolitinib

Responses often maintained after drug withdrawal, long-term persistence with ongoing treatment

AAD over a photo of Ernest N. Morial Convention Center in New Orleans, Louisiana.

Rapid Improvement in Atopic Dermatitis With Topical PDE4 Inhibitor

Disease status, itch improved significantly within 1 to 2 weeks with roflumilast cream

A photo of a shocked-looking woman looking at the hair on her brush.

Cases of Bald Spots After Regular Use of Detangling Hairbrushes

A report of three cases of trichomalacia in young women

AAD over a photo of Ernest N. Morial Convention Center in New Orleans, Louisiana.

Response Rates in Hidradenitis Suppurativa Continue to Climb With New Therapies

New analyses show "unprecedented" rates of 50% to 100% improvement

AAD over a photo of Ernest N. Morial Convention Center in New Orleans, Louisiana.

Another Win for a JAK Inhibitor in Alopecia Areata

About 40% of patients go from nearly hairless to almost a full head of hair with deuruxolitinib

A photo of the vial and packaging of Saphnelo over a photo of a woman’s face with discoid lupus erythematosus

New Lupus Drug Cuts Skin Disease When Other Agents Fail

Small study backs anifrolumab for salvage therapy

An illustration of a physician holding a patient's hand with the text The Doctor's Art - A podcast on Meaning in Medicine

Shaping American Medicine

Jack Resneck Jr., MD, on the future of healthcare

A photo of a man scratching his back which has computer rendered papules on it.

Strange Asymptomatic Rash Affects Young Man With Obesity for 2 Years

Diagnosis implicates high triglycerides as a contributor

Image of a hand with a bleeding fingernail

Make the Diagnosis: Do Not Blame the Manicurist

A 59-year-old woman visited her doctor concerned about a painful skin lesion near her fingernail that had developed over the past week.

A person's arm with furunculosis

Make the Diagnosis: Why Are These Lumps Here?

A 33-year-old woman went to the doctor after noticing painful lumps on her legs that had developed over the past few days, some of which had begun to drain pus. Can you diagnose the patient?

A photo of a Black woman scratching her palm which is affected by eczema.

Childhood Eczema Rose in Past Two Decades, With Unexplained Racial Divides

Black and multiracial children had the greatest increases in eczema

A photo of the packaging and auto injector of Dupixent over a photo of a man with atopic dermatitis on his hands.

Dupilumab Delivers in Erythrodermic Atopic Dermatitis

Key clinical outcomes, inflammatory biomarkers significantly reduced with or without steroids

Person's arm with a rash all over it.

Make the Diagnosis: Are These Cutaneous Eruptions Related to Her Landscaping Work?

A 46-year-old, immunocompetent commercial landscaper in Brazil presented to the doctor with an evolving eruption that had developed on her hand and spread to her forearm over the past few weeks. Can you diagnose the patient?

A photo of a woman scratching her back.

Oral Drug Shows Benefit for Notalgia Paresthetica in Mid-Stage Trial

Phase II study hits primary endpoint, but researchers call for larger and longer trials

A photo of a vial of the Spikevax COVID vaccine

Moderna Booster Vaccine Singled Out for Chronic Hives

Chronic spontaneous urticaria more frequent when compared with Pfizer's mRNA vaccine

A photo of a young woman with alopecia areata

High Rates of Psychiatric Disorders in Patients With Alopecia Areata

Two to three times higher than the general population, many more with suggestive symptoms

A photo of a woman in a gynecological chair.

Woman Seeks Answers After 3 Years of Painful Genital Ulcers

Histopathology reveals a disease most often seen in young children

A photo composite of a man with arm sores.

What Caused a Man to Develop Friable Bleeding Nodules on His Arms and Hips?

The cause lies in a lengthy history of cancer treatment, confirmed by histopathology analysis

A photo of a woman's hands affected by atopic dermatitis.

IL-13 Blocker Beats Atopic Dermatitis

With favorable results from three trials, approval seems likely

A close-up photo of a male physician and businessman shaking hands.

There's More Clinician Replacement at Practices Acquired by Private Equity

These practices also saw increases in advanced practice providers versus those not acquired

Photo of a person with Lupus Panniculitis

Make the Diagnosis: What Caused These Ulcerating Lesions in a Patient With SLE?

A 41-year-old woman with a history of systemic lupus erythematosus presented for evaluation of painful areas that had developed on her upper, outer arms and lateral thighs over the past month. Can you diagnose the patient?

INVESTIGATIVE ROUNDUP over an image of two people looking at computer screens.

UCSF's Unethical Experiments; Mystery of Doc Lost at Sea; Ketamine Via Telehealth

This past week in healthcare investigations

A photo of a mature man using two mirrors to see his bald spot.

5-ARIs Not Linked to Risk of Dementia Over the Long Term

However, finasteride and dutasteride were associated with an increased risk of depression

Photo of an arm with poison ivy

Make the Diagnosis: This Rash? Don’t Blame the Dog

A 23-year-old woman visited urgent care for a severely pruritic rash that had developed on her leg a couple of days prior and was spreading. Can you diagnose the patient?

A photo of a mom holding her daughter who is suffering from dystrophic epidermolysis bullosa

Topical Gene Therapy Heals Blistering Skin Disease Lesions

Randomized trial shows "dramatic" benefits in rare genetic disease

A computer rendering of a T cell attacking a cancer cell.

mRNA Cancer Vaccine Shows Promise in Early Trial

Melanoma patients who had vax plus PD-1 inhibitor did better than those on pembrolizumab alone

Close-up image of young boy with perioral dermatitis

Make the Diagnosis: Ring Around His Mouth: Why?

A 7-year-old boy was brought to the doctor by his mother regarding a facial rash that had developed over the past few weeks. Can you diagnose the patient?

A photo of a boy with reddened eyelids blowing his nose

What's Behind Boy's Bullous Skin Lesions After Flu Symptoms?

Mycoplasma pneumonia identified as the culprit in this case of RIME

A photo of a vaccine carrying freezer containing vials of Moderna, Janssen and Pfizer/BioNTech COVID vaccines

Large U.S. Study Finds No Link Between COVID Vaccine and Shingles

Findings add new evidence to conflicting prior reports

ACAAI over a photo of Kentucky International Convention Center in Louisville, Kentucky

New Treatment Options on the Horizon for Chronic Spontaneous Urticaria

Monoclonal antibodies, BTK inhibitor alleviate symptoms when antihistamines fall short

AASLD in text over an image of the Washington Convention Center.

Maralixibat Takes Out the Itch of Rare Liver Disease

Ileal bile acid transporter inhibitor could become second drug for PFIC

A photo of a woman with dermatitis on her stomach

Make the Diagnosis: What Triggered These Lesions?

A 55-year-old woman visited her doctor concerned about a mildly pruritic rash that had developed on her trunk and arms over the past few weeks. Can you diagnose the patient?

A photo of a young boy with Hunter Syndrome.

Pebbled Skin and Excessive Hair Growth on a 5-Year-Old's Back

Just two of the multiple symptoms that began to emerge shortly after birth

A photo of a woman with prurigo nodularis on the back of her hands.

Dupilumab Gets First FDA-Approved Indication for Prurigo Nodularis

Significant improvement in itch and nodules at 24 weeks seen in two randomized trials

VisualDx image of Anetoderma

Make the Diagnosis: His Skin Is Slacking Off

A 43-year-old man presented to the doctor with a rash that had developed on his trunk over the last couple of days.

A photo of a senior man talking on the phone with a pen in his hand hovering over a planner.

Appointment Wait Times Continue to Rise Amid Concerns of Physician Shortages

New survey finds that wait times increased by 8% across four specialties since 2017

Top of persons head with hair loss

Make the Diagnosis: Increased Hair Loss and 'White Bulbs' -- What’s Up?

A 55-year-old woman visited her doctor after noticing that the hair on her scalp was falling out at an increased rate over the last 3 months.

A photo of a senior woman touching her cheek

What Caused This Rapidly Enlarging Facial Abscess?

Expansion over several weeks necessitated timely diagnosis and ruling out mimicking conditions

EADV over a photo of the MiCo Milano Convention Center in Milano, Italy

Inflammation Marker May Spot Atopic Dermatitis Risk Early in Childhood

Elevated TARC at 2 months more than quadrupled the likelihood of moderate-severe AD at 2 years

A photo of silhouetted business people in a glass conference room with a city view.

Increased Health Spending When Private Equity Acquires Physician Practices

Patient volume also increased, but whether patients are benefiting remains to be seen

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