Dermatology

News, opinions and meeting coverage in dermatology.

FDA APPROVED retifanlimab (Zynyz) over a photo of a woman with Merkel cell carcinoma on her ear

FDA OKs Another PD-1 Inhibitor for Merkel Cell Carcinoma

Retifanlimab produced responses in 52% of patients with untreated unresectable disease

AAD over a photo of Ernest N. Morial Convention Center in New Orleans, Louisiana.

Durable Vitiligo Responses With Topical Ruxolitinib

Responses often maintained after drug withdrawal, long-term persistence with ongoing treatment

AAD over a photo of Ernest N. Morial Convention Center in New Orleans, Louisiana.

High Rates of Psoriasis Clearance With Investigational TYK2 Inhibitor

Rates of 90% clearance approaching 50% at 12 weeks, with 100% clearance rates as high as 33%

AAD over a photo of Ernest N. Morial Convention Center in New Orleans, Louisiana.

Rapid Improvement in Atopic Dermatitis With Topical PDE4 Inhibitor

Disease status, itch improved significantly within 1 to 2 weeks with roflumilast cream

A photo of a shocked-looking woman looking at the hair on her brush.

Cases of Bald Spots After Regular Use of Detangling Hairbrushes

A report of three cases of trichomalacia in young women

AAD over a photo of Ernest N. Morial Convention Center in New Orleans, Louisiana.

Response Rates in Hidradenitis Suppurativa Continue to Climb With New Therapies

New analyses show "unprecedented" rates of 50% to 100% improvement

AAD over a photo of Ernest N. Morial Convention Center in New Orleans, Louisiana.

Another Win for a JAK Inhibitor in Alopecia Areata

About 40% of patients go from nearly hairless to almost a full head of hair with deuruxolitinib

AAD over a photo of Ernest N. Morial Convention Center in New Orleans, Louisiana.

Biologic Switch Revs Up Response in Plaque Psoriasis

"Dramatic improvement" at 16 weeks with IL-23 blocker after lack of response to anti-IL-17 drug

A photo of the vial and packaging of Saphnelo over a photo of a woman’s face with discoid lupus erythematosus

New Lupus Drug Cuts Skin Disease When Other Agents Fail

Small study backs anifrolumab for salvage therapy

An illustration of a physician holding a patient's hand with the text The Doctor's Art - A podcast on Meaning in Medicine

Shaping American Medicine

Jack Resneck Jr., MD, on the future of healthcare

A photo of a man scratching his back which has computer rendered papules on it.

Strange Asymptomatic Rash Affects Young Man With Obesity for 2 Years

Diagnosis implicates high triglycerides as a contributor

Image of a hand with a bleeding fingernail

Make the Diagnosis: Do Not Blame the Manicurist

A 59-year-old woman visited her doctor concerned about a painful skin lesion near her fingernail that had developed over the past week.

Morning Break over illustration of a syringe, Covid virus, and DNA helix over a photo of green vegetation.

Biden's Skin Cancer; 'Butt Lift' Deaths Continue; Arrest Warrant for TB Patient

Health news and commentary from around the Web gathered by MedPage Today staff

A close up photo of a man’s forehead affected by actinic keratosis

Vitamin B3 Doesn't Cut Skin Cancer Risk After Organ Transplant

Randomized study finds no benefit with 12 months of nicotinamide versus placebo

A photo of a woman with knee joint effusion from psoriatic arthritis

Psoriatic Arthritis: Depressing News on Second- and Later-Line Treatments

Real-world data indicate most patients who fail a first biologic drug never obtain remission

A person's arm with furunculosis

Make the Diagnosis: Why Are These Lumps Here?

A 33-year-old woman went to the doctor after noticing painful lumps on her legs that had developed over the past few days, some of which had begun to drain pus. Can you diagnose the patient?

A photo of a Black woman scratching her palm which is affected by eczema.

Childhood Eczema Rose in Past Two Decades, With Unexplained Racial Divides

Black and multiracial children had the greatest increases in eczema

A photo of President Joe Biden in the Oval Office with his dogs Champ and Major

President Biden 'Remains Fit for Duty,' His Doctor Says

Routine physical finds stiffened gait a result of osteoarthritis, but no treatment needed

A photo of the packaging and auto injector of Dupixent over a photo of a man with atopic dermatitis on his hands.

Dupilumab Delivers in Erythrodermic Atopic Dermatitis

Key clinical outcomes, inflammatory biomarkers significantly reduced with or without steroids

Person's arm with a rash all over it.

Make the Diagnosis: Are These Cutaneous Eruptions Related to Her Landscaping Work?

A 46-year-old, immunocompetent commercial landscaper in Brazil presented to the doctor with an evolving eruption that had developed on her hand and spread to her forearm over the past few weeks. Can you diagnose the patient?

A photo of a woman scratching her back.

Oral Drug Shows Benefit for Notalgia Paresthetica in Mid-Stage Trial

Phase II study hits primary endpoint, but researchers call for larger and longer trials

A computer rendering of an LDL receptor.

Targeting Specific Lipid Metabolic Pathway Linked to Reduced Psoriasis Risk

Genetics study suggests potential for precision medicine approach with PCSK9 inhibitors

A photo of a vial of the Spikevax COVID vaccine

Moderna Booster Vaccine Singled Out for Chronic Hives

Chronic spontaneous urticaria more frequent when compared with Pfizer's mRNA vaccine

A photo of a young woman with alopecia areata

High Rates of Psychiatric Disorders in Patients With Alopecia Areata

Two to three times higher than the general population, many more with suggestive symptoms

A photo of a woman in a gynecological chair.

Woman Seeks Answers After 3 Years of Painful Genital Ulcers

Histopathology reveals a disease most often seen in young children

A photo composite of a man with arm sores.

What Caused a Man to Develop Friable Bleeding Nodules on His Arms and Hips?

The cause lies in a lengthy history of cancer treatment, confirmed by histopathology analysis

Morning Break over illustration of a syringe, Covid virus, and DNA helix over a photo of green vegetation.

Jill Biden's Cancer Surgery; Gurney Suffocation Death; Dollar General Clinics

Health news and commentary from around the Web gathered by MedPage Today staff

A photo of a woman's hands affected by atopic dermatitis.

IL-13 Blocker Beats Atopic Dermatitis

With favorable results from three trials, approval seems likely

A close-up photo of a male physician and businessman shaking hands.

There's More Clinician Replacement at Practices Acquired by Private Equity

These practices also saw increases in advanced practice providers versus those not acquired

Photo of a person with Lupus Panniculitis

Make the Diagnosis: What Caused These Ulcerating Lesions in a Patient With SLE?

A 41-year-old woman with a history of systemic lupus erythematosus presented for evaluation of painful areas that had developed on her upper, outer arms and lateral thighs over the past month. Can you diagnose the patient?

INVESTIGATIVE ROUNDUP over an image of two people looking at computer screens.

UCSF's Unethical Experiments; Mystery of Doc Lost at Sea; Ketamine Via Telehealth

This past week in healthcare investigations

A photo of a mature man using two mirrors to see his bald spot.

5-ARIs Not Linked to Risk of Dementia Over the Long Term

However, finasteride and dutasteride were associated with an increased risk of depression

A close up photo of a man’s hand with IV lines attached to it, clutching the pole of the IV bag hanger.

Can Biomarkers Give Early Heads-Up on Immune Checkpoint Inhibitor Myocarditis?

Early research on detecting serious side effect of cancer therapy

Photo of an arm with poison ivy

Make the Diagnosis: This Rash? Don’t Blame the Dog

A 23-year-old woman visited urgent care for a severely pruritic rash that had developed on her leg a couple of days prior and was spreading. Can you diagnose the patient?

Bottles of Braftovi and Mektovi tablets over a photo of advanced melanoma

Long-Term Data Reinforce Targeted Combo Versus Single Agent for Advanced Melanoma

Encorafenib-binimetinib tops vemurafenib, but checkpoint inhibitors remain first-line choice

A photo of a mom holding her daughter who is suffering from dystrophic epidermolysis bullosa

Topical Gene Therapy Heals Blistering Skin Disease Lesions

Randomized trial shows "dramatic" benefits in rare genetic disease

A computer rendering of a T cell attacking a cancer cell.

mRNA Cancer Vaccine Shows Promise in Early Trial

Melanoma patients who had vax plus PD-1 inhibitor did better than those on pembrolizumab alone

Morning Break over illustration of a syringe, Covid virus, and DNA helix over a photo of green vegetation.

mRNA Cancer Vaccine Shows Promise; Sounding the Strep A Alarm; Phasing Out Tobacco

Health news and commentary from around the Web gathered by MedPage Today staff

Drug, Alcohol Deaths in Those Over 65; Medicare Advantage and Heart Attacks

Also in TTHealthWatch: a new therapy for advanced melanoma

Close-up image of young boy with perioral dermatitis

Make the Diagnosis: Ring Around His Mouth: Why?

A 7-year-old boy was brought to the doctor by his mother regarding a facial rash that had developed over the past few weeks. Can you diagnose the patient?

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