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AAN

Brain Structure, Widespread Connectivity Changes Seen With Long COVID

Gray matter atrophy, hyperconnectivity in patients with anxiety, depression

Keto Diet Bettered Fatigue, Depression in MS

Quality of life, disability showed improvements in phase II study

CDKL5 Deficiency Disorder Drug Data Support Modest Benefit

Success in rare epileptic disorder may presage broader approvals

Trial May Set Standard for Steroid Therapy in Duchenne Muscular Dystrophy

Daily dosing tops 10-day on/off cycles

Migraine Tied to Pregnancy Complications

Preeclampsia, gestational hypertension associated with pre-pregnancy migraine

Novel Drug Reduces Tics in Kids With Tourette Syndrome

Ecopipam shows promise in phase II study

Memory Enhancer Succeeds in Phase II Alzheimer's Trial

Novel NMDA-targeted drug would expand options for symptomatic treatment

Polypill Looks Good for Parkinson's

Fixed-dose product combining two standard drugs outperforms each alone in phase III

Trofinetide Shows Promise in Rett Syndrome

Investigational drug demonstrates modest benefit for primary, secondary endpoints

Myasthenia Gravis: Better Version of Eculizumab on the Horizon

Phase III study paves way for new ravulizumab indication

Novel Wrinkle on Botulinum Toxin Succeeds for Cervical Dystonia

Formulated for longer activity, symptoms stay suppressed until time for next dose

Stroke While on LVAD No Barrier to Successful Heart Transplant

It doesn't help, for sure, but it doesn't seem to hurt greatly either

Prion Disease on the Rise in the U.S.

Now the question is, why?

Persistent Brain Fog After Mild COVID Infection Tied to CSF Markers

Immune activation, immunovascular markers elevated in people with long COVID cognitive changes

Could Undiagnosed Neuro Condition Explain Grandpa's Falls?

Peripheral neuropathy found in many patients who weren't aware of it

Endovascular Brain-Computer Interface Safe, Effective in ALS

No serious adverse events with novel device at 1 year

Tic Severity in Teens Rises With Social Media Use During Pandemic

Study adds to findings linking tics and tic-like behaviors with possible pandemic stress

Owning a Pet May Protect Cognitive Health

Strongest benefit seen for long-term pet owners

Alzheimer's Aducanumab Redosing Study Underway

Nearly 1,400 patients whose treatment was stopped when trials were halted have enrolled

Novel Oxybate Tx Helps Idiopathic Hypersomnia Patients

Lower-sodium oxybate improves scores on sleepiness scale compared with placebo

Human IgG1 Antibody Shows Promise in Myasthenia Gravis

Phase III study shows improvements in activities of daily living

BTK Inhibitor Cuts Marker of Neuronal Damage in Relapsing MS

Novel agent lowered neurofilament light chain levels, may help reduce neuroaxonal damage

Vaccines and Long COVID: Top NIH Leaders Weigh in at Neurology Meeting

Can research on long COVID help people with chronic fatigue?

Black MS Patients See More Rapid B-Cell Repopulation

May have implications for timing of lab draws and anti-CD20 dosing, researchers say

Novel ALS Drug Continues to Show Survival Benefit

Median time to first hospitalization not yet reached with AMX0035 in CENTAUR trial

COVID Antibody Responses Reduced in Some MS Patients

But T-cell responses were similar, even in patients on ocrelizumab

COVID Deaths Higher With Neuro Syndromes in Hospitalized Patients

Encephalopathy, coma most prevalent neurologic manifestations

Global Stroke Care Takes a Hit During the Pandemic

Seventy-country study finds ties to drop in volume of stroke hospitalizations, treatment

Blood-Based Markers Tied to Brain Cell and Memory Loss

Another step closer to clinical utility for tracking neurodegeneration

COVID Stroke Rare in ICU

Ischemic stroke in intensive care didn't raise mortality, but hemorrhagic stroke did

New-Onset Neuro Symptoms Common in Kids With MIS-C

Half of pediatric patients in small British study show neurologic involvement

Cannabis Tied to Rebound Headaches in Chronic Migraine Patients

Study adds to findings about marijuana and migraine

Alzheimer's May Start Sooner for People With Anxiety, Depression History

Psychiatric disorders could have additive effects on AD pathophysiology, study suggests

How Long Do COVID Olfactory Problems Last?

Sense of smell can be altered for 5 months or longer, Canadian study suggests

Leukemia Drug for Parkinson's: A Second Look

Are there better ways to inhibit c-Abl?

Ozanimod Treatment Duration and Infection Risk

Zoster rates low, but rising with time

At-Home Myasthenia Gravis Therapy Shows Promise

Zilucoplan improves neuromuscular symptoms in phase II trial

Novel Drug Cocktail Offers Rare Neuropathy Patients New Hope

Charcot-Marie-Tooth patients see improved outcomes with repurposed drugs

New Thinking on Stiff Person Syndrome -- Or Is It Syndromes?

Heterogeneity complicates the picture; rituximab, bortezomib get love for refractory cases

Oral CGRP Drug Bests Placebo for Migraine Prevention

Atogepant was effective, safe, and well-tolerated

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