EASL

Small fazirsiran trial sees fibrosis regressions for liver disease associated with AAT deficiency

Randomized trial showed improvements in cardiometabolic markers, but not liver fibrosis

37% higher risk observed in large German study

Nearly half of patients at week 48 had virological and biochemical response

14% of patients experienced a reinfection over the past decade

Danish study shows fibrosis screening associated with improved diet, alcohol use, and exercise

Small preliminary trial also shows hints of promising clinical results

Real-world study also identifies noninvasive markers for treatment response

Social determinants of health play a key role, study found

U.K. study confirms it's mainly mom's fault

"Safe and successful conversion therapy" with hepatic arterial infusion chemo plus sintilimab

But expert questions conclusion of small study from Spain

Significant responses seen with novel agent for "devil" disease

Long-term impact of alcohol uptake on liver health during COVID-19 crisis remains unknown