Misfolded prion protein was detectable in tear fluid of people with Creutzfeldt-Jakob disease. (New England Journal of Medicine)
Autologous hematopoietic stem cell transplants showed benefit over fingolimod (Gilenya) and natalizumab (Tysabri) in relapsing multiple sclerosis (MS), but not ocrelizumab (Ocrevus), in observational data. (JAMA Neurology)
Reduced slow-wave sleep and severe obstructive sleep apnea were associated with higher burden of white matter abnormalities in predominantly cognitively unimpaired older adults. (Neurology)
Expert video assessments suggested it might not be possible to distinguish primary from functional tics reliably based on phenomenology alone. (Journal of Neurology, Neurosurgery & Psychiatry)
If the Alzheimer's drug lecanemab (Leqembi) wins traditional FDA approval, its cost to Medicare may be an estimated $2 to $5 billion a year. (JAMA Internal Medicine)
COVID-19 induced neuroinflammation and suppressed peroxisomes in the brain, tissue and cell samples showed. (Annals of Neurology)
Abbott received approval for its spinal cord stimulators to treat nonsurgical back pain, the company said.
In adults with a first single unprovoked seizure, 24-hour ambulatory electroencephalography (EEG) had increased sensitivity compared with routine and repeated EEG. (Neurology: Clinical Practice)
A predictive network analysis identified 10 neuronal key drivers of the Alzheimer's-associated network state, which may represent therapeutic targets. (Communications Biology)
Multiparametric quantitative MRI showed progressive cortical damage in clinically stable relapsing-remitting MS. (Journal of Neurology, Neurosurgery & Psychiatry)