Bystander Defibrillation; More Balloon Pumps Recalled; Best Statin-Aspirin Combo

— Recent developments of interest in cardiovascular medicine

MedpageToday
Cardio Break over a computer rendering of a heart.

Survival and 1-year outcomes after out-of-hospital cardiac arrest were best when initial defibrillation was provided by bystanders, not paramedics. (Heart)

FDA revised its guidance on the Janssen COVID-19 vaccine to include a warning of myocarditis and pericarditis developing within 7 days of injection.

A sex-specific predictor of mortality after transcatheter aortic valve replacement (TAVR): mosaic loss of Y chromosome in blood cells of men. (European Heart Journal)

There is much center-level variation in TAVR costs in the U.S., and procedural volumes and complications could not explain this observation. (Annals of Thoracic Surgery)

Regarding the question of expanding transcarotid artery revascularization, patients with standard surgical risk who underwent the procedure had no worse composite clinical events at 1 year, albeit excess ipsilateral strokes, compared with peers who got carotid endarterectomy. (JAMA Neurology)

More Cardiosave Hybrid/Rescue intra-aortic balloon pump models are being recalled, this time for unexpected shutdowns related to cable failures between the display and base on some units, the FDA said.

One particular booklet managed to modestly improve cardiovascular clinical screening uptake among first-degree relatives of people with dilated cardiomyopathy. (Circulation)

Survey of pediatric cardiology fellowship directors suggests women are disproportionately dropping out of the training pipeline before reaching a faculty position. (Journal of the American College of Cardiology)

In a nationally representative cross-sectional study, U.S adults with normoglycemia and prediabetes improved their weight control between 2007-2008 and 2017-2018, but not those with diabetes. Total cholesterol fell for all three groups but remained elevated in prediabetes patients. (European Journal of Preventive Cardiology)

A look at how each U.S. state fared in closing racial gaps in cardiovascular mortality in two decades. (JAMA Cardiology)

Children living in deprived neighborhoods tend to have a greater likelihood of developing primary hypertension as youths. (JAMA Network Open)

Researchers introduced the concept of a biological BMI using multiomic profiling to identify molecular signatures of obesity. (Nature Medicine)

For the most effective cardiovascular disease prevention, the best statin to complement aspirin therapy may be rosuvastatin, according to observational data. (Scientific Reports)

Thiamine flopped as a neuroprotective agent in cardiac arrest in a pig study. (Journal of the American Heart Association)

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    Nicole Lou is a reporter for MedPage Today, where she covers cardiology news and other developments in medicine. Follow