Patterns of lifespan BMI changes may predict dementia risk, data from the Framingham Heart Study Offspring study suggested. (Alzheimer's & Dementia)
A dominantly inherited deep intronic GAA repeat expansion in FGF14 was associated with late-onset cerebellar ataxia. (New England Journal of Medicine)
The U.S. Department of Health and Human Services released the 2022 National Plan to Address Alzheimer's Disease, focusing on disparities and reducing dementia risks.
Researchers identified optimal deep brain stimulation sites and networks for investigational fornix stimulation in Alzheimer's disease. (Nature Communications)
Alzheimer's disease-like neuropathology was found in three species of oceanic dolphin. (European Journal of Neurology)
Genetic risk for attention-deficit/hyperactivity disorder (ADHD) predicted cognitive decline and Alzheimer's disease pathophysiology in cognitively unimpaired older adults. (Molecular Psychiatry)
Four mutations were associated with progressive multifocal leukoencephalopathy (PML), opening the possibility for genetic testing to screen multiple sclerosis patients who take PML-linked drugs. (Frontiers in Neurology)
Twelve-year neurocognitive decline in HIV was tied to comorbidities, not age, data from the CHARTER study showed. (Brain Communications)
Edmonton Frailty Scores were significantly associated with anti-seizure medication tolerability in older adults with epilepsy. (Neurology)
Nature Reviews Drug Discovery looked at Biogen and Denali's pivotal trial that began in October of an oral LRRK2 kinase inhibitor for Parkinson's disease.
Abbott announced FDA approval of its Eterna spinal cord stimulation system for chronic pain, saying it's the smallest rechargeable spinal cord stimulation implant for pain on the market.